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Colchicine is a drug for the treatment of gout, affecting the uric acid metabolism. Colchicine is used for acute attacks of gout (acute gouty arthritis), as well as in the periodic disease (familial Mediterranean fever), Behcet's disease, other acute attacks of Chondrocalcinosis.

Colchicine has some contraindications: hypersensitivity, the defeat of the gastrointestinal tract, acute liver and kidney failure, pregnancy and lactation.

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Colchicine is an arthrifuge used for the treatment of such diseases:

  • relief of acute gout attacks and prevention of repeated occurrences;
  • arthritis (gout);
  • chondrocalcinosis;
  • amyloidosis;
  • some phlebitis forms, scleroderma;
  • sextan fever;
  • inflammatory processes in otolaryngology and dentistry.

Colchicine has a positive effect on the skin, reducing dryness and softening the skin in scleroderma (systemic).

The drug is prescribed with caution for the elderly. The drug is not recommended for those who take alcohol regularly, and for people who have disorders of severe functionality of the cardiovascular system, bone marrow and the gastrointestinal tract, and kidney and/or liver failure in severe form. The drug shouldn't be taken during pregnancy.

Within 12 hours after Colchicine taking an improvement of more than three-quarters of the patients is observed.

About 80 percent of patients may have some side effects from the gastrointestinal tract, at the same time with improve or before it. In intravenous administration such phenomena from the gastrointestinal tract are absent, and the clinical effectiveness of the drug effect improves substantially.

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Medical professionals often advise people with gastroesophageal reflux disease (GERD) to cut caffeine from the diet. However, little scientific evidence suggests that everyone with GERD should avoid caffeine. Learn more here.

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